Romaco, an international supplier of processing and packaging equipment specializing in engineering technologies for pharmaceutical products, will display its latest tablet press for the high-speed sector at CPHI & PMEC India in November 2023.
The Kilian E 710 Smart double-sided rotary press for high-volume production is specifically tailored to the requirements of the Asian markets. The Ventilus Lab fluid bed processor from Romaco Innojet attached to an Innojet IHD 5 hot melt device, will be a further highlight at the exhibition.
From powder to finished pallet, Romaco covers the entire process chain for manufacturing and packaging pharmaceutical products. The solutions supplier specializes in sustainable machines and equipment aimed at reducing both carbon dioxide emissions and manufacturing costs in the pharmaceutical industry.
Romaco will take advantage of this year’s CPHI & PMEC India to show its latest development in the high-productivity tableting sector and demonstrate the enormous energy saving potential of its innovative fluid bed technology.
E 710 Smart double-sided rotary press from Romaco Kilian
The E 710 Smart expands Romaco Kilian’s product portfolio with a new double-sided rotary press that was particularly developed for high production volumes with low margins. This economical tablet press for mono- and bi-layer production is based on Kilian’s four-column design. The single-piece, deep-drawn process area ensures hermetical separation between the compaction and technical areas. A closed V-ring seal underneath the die table additionally prevents tablet dust from entering the ‘grey’ area, the company said in a release.
With between 51 and 85 press stations and a pitch circle diameter of 712 mm, the Kilian E 710 Smart achieves a maximum output of up to 1,020,000 tablets per hour. Brake magnets permit absolutely homogeneous filling of the dies without any wear on the punch shafts. Moreover, special Kilian bellows protect the tablets from contamination in the form of black spots. The fill shoe is quick and simple to clean because the gear is external.
Owing to the small number of interchangeable parts and the good accessibility to individual components, retooling and cleaning times are significantly reduced. The tablet scraper and chute are mounted together on a swivel arm for easy removal. Product loss is minimized thanks to the floating product scraper with magnets. The sparing use of natural resources is totally consistent with Romaco Kilian’s sustainability strategy.
Ventilus Lab fluid bed processor from Romaco Innojet
Designed for laboratory-scale applications, the Ventilus Lab fluid bed processor from Romaco Innojet is used for granulating, drying, and coating particles of any size from 10 µm to 2 mm. This multipurpose lab unit is intended for batch sizes from 0.7 to 7.0 liters. With its innovative process air distribution system inside the cylindrical product container, the Ventilus Lab shortens batch processing times by up to 25 percent because the required power can be used far more efficiently.
The process air is introduced through the circular Orbiter booster, ensuring homogeneous flow conditions and extremely gentle intermixing of the batch. In combination with the Rotojet, the central bottom spray nozzle, the Orbiter booster plate forms a unique functional unit enabling much simpler scale-up processes.
The patented fluid bed components invented by Dr. Herbert Hüttlin lie behind the remarkably accurate application of the spray liquid with a precisely defined droplet size. With controlled release formulations, for instance, the modified release profiles are achieved using 10 to 15 percent less material. This targeted reduction in spray liquid usage also means less power consumption, so that the Ventilus Lab results in substantially fewer carbon dioxide emissions from fluid bed processes. Furthermore, the rotating Sepajet filter system minimizes general product loss by returning particles retained by the filter to the process rather than discharging them.
IHD 5 hot melt device from Romaco Innojet
The innovative IHD 5 hot melt device from Romaco Innojet was developed for coating and granulating fine solid particles with organic fats or waxes. The fact that no evaporation takes place during the hot melt process, because the hot melt coatings contain no solvents and solidify as soon as they are sprayed, is a decisive advantage. Up to 85 percent shorter processing times are possible as a result and power consumption is significantly lower, especially since there is no need to heat the process air in order to dry the product.
Hot melt coatings are employed in the pharmaceutical, food, and nutraceuticals industries, where they function as a moisture barrier or a taste mask, for example for orally disintegrating granules. The hygienic design of Romaco Innojet’s IHD 5 – which is CIP-capable with no dead spaces – enables GMP-compliant cleaning and prevents cross contamination. The unit can be opened without difficulty, and so all product-contacted surfaces inside the hot melt device are clearly visible throughout.
In the interests of uniform heat distribution, the patented technology was designed as a heatable monobloc integrating all functional components including the valve block, dosing unit, and product container. The mobile IHD 5 is simply connected to the Rotojet spray nozzle of a Romaco Innojet Ventilus® fluid bed processor via a trace heated tube. Excellent product quality is ensured by the pulsation-free dosing of the melt coatings.
CPHI & PMEC India 2023 will be held from 28 to 30 November 2023 at India Expo Centre, in Greater Noida. Ro, Romaco will be present at Hall 10, Stand C03.
